Category Archives: Benzodiazepine

Caution: Street Oxycodone Might Be Fentanyl

Minnesota officers recently seized a large quantity of fentanyl in the Midwest based on extensive investigation and “very, very good police work”.

The drug bust removed enough fentanyl pills to kill over 1 million people, and the suspected dealer now faces federal charges for possessing a large quantity of synthetic opioids.

Of particular concern was that the fentanyl doses had been pressed into a familiar pill that was indistinguishable from that provided in a typical oxycodone prescription. So oxycodone obtained on the street now presents with a much higher risk of fatal overdose than was previously thought.

The article reported that large quantities of fentanyl continue to come across the U.S. southern border. The U.S. Senate is currently examining how this influx of fentanyl is impacting American communities as drug seizures hit historic levels.

Those currently struggling in active opioid addiction should explore getting professional help as soon as possible. Fentanyl “in disguise” is making its way across the country.

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Methadone and Other Medications

doc66Methadone is FDA-approved for pain management and the treatment of opioid addiction. Methadone is a relatively safe and highly effective medication when used exactly as prescribed. It is currently in use in the United States and around the world following years of conclusive research on methadone’s efficacy and safety.

It is important for patients receiving methadone to know that it can interact with other central nervous system depressants like alcohol and benzodiazepines such as xanax, klonopin, valium, and librium as well as similarly acting non-benzodiazepine agents like ambien (a popular sleep aid). When methadone is mixed with these other medications, there is an increased risk of sedation and loss of consciousness. In extreme cases, individuals mixing methadone and other CNS depressants have gone into respiratory failure.

For those who have chosen to receive methadone in an opioid treatment program, they will discover that a proper dose of methadone not only eliminates opiate withdrawal & cravings, but will also block the euphoric effects of any other opiates. This is typically a positive side effect in that it discourages illicit opiate use or supplementing with street drugs like heroin. Since methadone binds so well to the brain’s opiate receptor sites, any other opiates that are ingested have no means of creating a euphoria or a high since the body’s opiate receptors are occupied by methadone. This removes the incentive to misuse other opiates and can facilitate the process of recovery. I was ordered by his neuropathologist to treat panic attacks. I began to drink them in half, and then I kiss the pill for the night. I drank a tablet of hours at 8 pm – after half an hour I sleep with a child). The effect is very classy: nothing is interesting, nothing is needed, there is no emotion – everything a person needs is just morally tired.) She accepted Klonopin for about four months. The effect was. Somehow I just did not care about panic attacks). They did not care anymore.

There are instances in which a patient’s physician has prescribed a benzodiazepine for anxiety management while also prescribing methadone. Such decisions should always be accompanied by a thorough discussion with one’s doctor of the potential risks & complications. There are other, safer alternatives for treating anxiety such as Buspar and cognitive therapy. These other options should be considered when a patient is already receiving methadone. In addiction treatment, the use of benzodiazepines for anxiety is typically monitored carefully through increased random urinalysis testing and medication counts.

Benzodiazepines in the Methadone Program

factsBenzodiazepines are a classification of drugs primarily prescribed to treat anxiety and panic attacks. They have been in use for over thirty years and are typically utilized for short term periods from several days to three months maximum.

Benzodiazepines are sometimes administered just prior to medical procedures or surgery to help calm a patient. Common examples include valium, ativan, klonopin, librium, and xanax. These medications have also been used successfully on a short-term basis to help reduce alcohol withdrawal as patients undergo alcohol detoxification.

For opioid treatment programs, benzos present a particular risk due to the higher probability of abuse and overdose death when mixed with methadone, other opioids, or alcohol. Benzodiazepines depress the central nervous system and can shut down respiration when combined with other CNS depressants. This lethal drug combination has resulted in numerous accidental deaths – even among experienced drug users.

While limited and carefully monitored benzodiazepine use can be clinically justified in some cases, prescribing physicians (and methadone clinics) must be vigilant and cautious in their use of these medications due to their risk of abuse and overdose with opioid dependent patients.

Many opioid treatment programs around the country have adopted a no benzodiazepine policy and will not induct a patient with methadone until the patient has successfully detoxed off of any benz medications, and is able to test negative for the drug.

Some prospective patients have been on benzodiazepines for many years – long past any justifiable therapeutic or medical necessity. Several years ago, an OTP was approached by a client seeking admission who had been taking klonopin by prescription for 25 years. She had experienced several overdose episodes during that time period. The prospective patient voluntarily completed a successful detox off the klonopin, and she demonstrated incredible courage in pursuing this goal. She remained benz free and has tested negative for illicit substances for 3 years now. While she was afraid and doubtful that she could complete the benz detox, she surprised herself and the clinic staff in what can only be described as an incredible commitment to change and a new life.

For those patients diagnosed with a severe anxiety disorder, benzodiazepines may be indicated in select cases. Cognitive-behavioral therapy can also be effective in helping individuals learn to cope successfully with anxiety although it will require strong commitment to the therapy process and a considerable degree of work. With benzodiazepine treatment alone, the medication only manages the symptoms … but does not treat the underlying cause of the anxiety. For that reason, treating anxiety exclusively with benzodiazepines (at the exclusion of therapy) can be a disservice to a patient. Take care with how long you take , it might be way more difficult to detoxify if you take up the habit. It’s even more difficult than with other less socially acceptable drugs. Also, never exceed the dose. By the example of a friend of mine I learned that your withdrawal syndrome could last for months.

Physical dependency on benzodiazepines can be quite powerful and withdrawal from them dangerous. No one should ever try to self-detox from a benzodiazepine addiction due to the risk of seizure and possibly death.

Methadone Programs and Prohibited Medications

rx-medication-abuseMany clients in methadone programs have co-occurring disorders like depression, anxiety, or adult attention deficit disorder (ADD). Historically, clinics have attempted to treat psychiatric symptoms with established, FDA-approved psychotropic medications which have proven useful across many settings in managing symptoms.

In the past decade, it became very apparent that benzodiazepines (commonly prescribed to treat anxiety) had become a popular alternative drug of abuse for individuals with an opioid addiction. “Benzos” are a particularly dangerous medication when used in conjunction with methadone, and the combination of these two contributed to a number of overdose deaths in recent years.

For this reason, many safety-oriented, reputable methadone clinics (and independent physicians) either discontinued or noticeably restricted their use of benzodiazepine medications with patients on methadone. Common benzodiazepines include prescription meds like klonopin, valium, xanax, and ativan. As an alternative to these high risk medications, non-addictive options like Buspar are utilized to help clients better manage their anxiety symptoms as well as cognitive therapies for teaching stress reduction and anxiety management skills.

Stimulant therapy is the use of stimulant-based medications to aid adults struggling with attention deficit disorder. Popular medications in this class include adderall, ritalin, and concerta. Unfortunately, these medicines are also widely abused and often illegally sold by patients thus forcing treatment providers to reconsider the use of these medications in their programs.

Positively, there are several medications which can help ADD and which have a low abuse potential. Some psychotropic medications can also be used off label to help reduce attention deficit problems. Off label means the drug was not designed specifically to treat a symptom, but has been found to have a beneficial effect on reducing that symptom.

In the end, methadone programs must employ the safest protocols to insure that clients receive treatment that genuinely helps them and will not place them at risk. There are instances in which benzodiazepines and stimulant therapies are appropriate and in the best interest of the client. However, medical and clinical staff must utilize a careful sense of discretion and evaluate the merits of a particular high risk medication against its potential for harm.

Clients can help this process by being open, honest, and direct with their treatment staff. Clients should report to management any person who is known to sell prescription medications to other clients. While this type of behavior typically occurs among a minority, it can have an extremely negative impact on other clients and the clinic itself.

Prescription Monitoring Helps Suboxone and Methadone Treatment

methadone40Dr. Jana Burson, in her opioid treatment blog, has written two important and interesting entries on the value of prescription monitoring programs (entry 1, entry 2). Prescription monitoring allows approved physicians to review a database listing controlled substances a patient receives (like opioids or benzodiazepines), the prescribing physician, and the pharmacy that filled the prescription.

This information is extremely useful for monitoring patient behavior in opioid treatment and helping to provide a measure of patient accountability. Some patients have a pattern of doctor shopping and abusing prescription medications even after entering opioid treatment. This monitoring program allows doctors to identify doctor shopping activities and to intervene with their patients who may be abusing prescription meds or selling them.

Dr. Burson writes that 42 states have approved a prescription monitoring program, and a majority of them already have the program up and running in their state. One notable exception is the state of Florida. Dr. Burson writes that Florida’s Governor Scott has blocked the implementation of the prescription monitoring program. This is detrimental to identifying & managing prescription abuses across the state. It is reported that Governor Scott has been contacted by other State Governors urging him to reconsider.

Methadone and suboxone treatment programs aim to help their clients change their lifestyle & behavior, and to make choices rooted in healthy recovery. Prescription monitoring enables treatment professionals to assist their clients in examining negative behaviors and correcting them.

Some individuals who doctor shop find themselves in legal trouble and facing possible incarceration. This can derail a client’s opioid treatment, as well as compromise the integrity and reputation of the methadone treatment program trying to serve addicted people. It is much better to identify prescription abuses early on and to intervene quickly.

Prescription monitoring programs are ideal for the safety and security of clients and the welfare of communities. The over-prescribing of opioids and benzodiazepines has become a major problem in the United States, and prescription monitoring is a huge forward step in rectifying this troubling issue.