Tag Archives: methadone safety

Buprenorphine and Liver Health

methadone-safe-for-liverJana Burson is a North Carolina physician who specializes in the treatment of opioid addiction using medications like buprenorphine and methadone. Dr. Burson is a passionate caregiver and patient advocate with considerable experience in the field of addiction treatment. She maintains an informative blog on the topic of opioid addiction treatment and recently posted her comments and observations on a revealing 2012 study.

The 2012 study by Saxon et al is reported in her blog to have followed more than 700 patients over 24 weeks who were receiving either methadone or buprenorphine (the active ingredient in Suboxone). These patients were checked for specific red flag elevations that would suggest emerging liver damage or liver inflammation. None of the patients receiving methadone or buprenorphine had significant abberations in liver functioning. This led the researchers to conclude that neither medication causes liver damage.

A 2014 follow-up study by Soyka and others (published in the American Journal on Addictions) found the same results in their research of 181 patients on Suboxone (buprenorphine + naloxone).

Studies like these help to dispel misinformation around opioid treatment medications and their safety. Dr. Burson expressed that it was once routine to order liver function tests for patients on buprenorphine therapy, but that this is likely unnecessary given the more recent research validating methadone and buprenorphine’s safety in regard to liver functioning.

There are addiction-related illnesses, like Hepatitis C, that can have highly detrimental effects on the liver. According to Dr. Burson, the Soyka study also showed that buprenorphine was not harmful even in patients diagnosed with Hepatitis C.

Thorough research studies like these are important in further legitimizing the benefits & established safety profile of opioid treatment medications. Having access to safe medications helps hundreds of thousands of people find effective treatment for chronic opioid addiction.

For More On Methadone

Pregnancy and Opioid Treatment

pregnancyWhen a woman is pregnant and addicted to opioids, she faces extraordinary stress and very often a wave of judgment from those around her that is emotionally painful and difficult to deal with. The criticism of others is understandable since no one wants to see an unborn baby placed at risk through the mother’s drug use. But this cauldron of angry emotion and public condemnation often overwhelms a pregnant mother, who may already feel guilty, and it pushes her further into isolation and inaction. This isolation only places the mother and unborn baby at greater risk of overdose and possible miscarriage.

Fact: It has been thoroughly researched and the findings conclusive that pregnant opioid-addicted women have a much better chance of carrying their baby to term and having a healthy baby when the mother is receiving medication-assisted treatment. Every day, addicted mothers receiving methadone or buprenorphine give birth to healthy babies that thrive and develop normally.

Methadone and buprenorphine (Subutex) are very different medications compared to heroin and painkillers like oxycodone. Heroin and painkillers manufactured for break-through pain act quickly, but also dissipate quickly. For those with an opioid addiction, this momentary relief from opioid withdrawal does not last long and they are back out there again desperately trying to find more heroin to avoid becoming sick.

With methadone or buprenorphine, mothers are medically stable and able to avoid debilitating cycles of withdrawal as well as the dangerous drug-seeking behaviors and lifestyle that put them and the baby at risk. A woman is already in a state of increased vulnerability when pregnant. If lonely, isolated and forced to go to the street to find dope or pills, she will find herself in dangerous situations and exposed to a drug culture that values money over human life.

This harsh reality is what some women face as they struggle to survive while carrying an unborn child. If in treatment at a methadone clinic or under the supervision of a caring physician who utilizes buprenorphine, the pregnant woman can start the process of personal recovery. She can avoid becoming sick from opioid withdrawal and avoid taking grave risks just to avoid that withdrawal. She can receive emotional support and medical assistance to maximize her health and that of the unborn baby. She can better prepare herself to be a good mom once the baby is born.

There are those who may indignantly exclaim “But the baby will be born addicted”. The reality is that it is much safer for a baby to be born to a mother receiving methadone or buprenorphine than for the baby to be repeatedly exposed to adulterated street heroin and combinations of drugs riddled with unknown contaminants. Think about that. Technically, the baby may be born with some physical dependency, but this is successfully managed all the time by medical professionals across the country. Buprenorphine has been found to have a milder withdrawal syndrome and is utilized successfully in helping infants comfortably detox. Methadone is successfully used for this purpose as well.

It is important to also make a distinction between “addiction” and “dependency”. They are not the same. “Addiction” encompasses the persistent craving for opiates, the mental preoccupation with securing them, and the inappropriate behaviors and lifestyle aberration that develop as people lose control over their ability to choose. “Dependency” can occur with anyone who has been using an opioid for a sustained period of time. Someone who has become “dependent” can readily taper off of the medication and will not be necessarily driven to obsess over drugs or desperately seek them. A baby who is born temporarily dependent on methadone or buprenorphine can be successfully tapered off of the medication. Obviously, a baby does not meet the definition of “addicted” so to use that term is technically inaccurate and misleads the public.

Finally, methadone and buprenorphine are safer for the baby. It’s ultimately about helping that unborn baby to develop normally in the womb and to be born alive, healthy, and with maximum opportunity for a good life. Chances are that the mother will indeed be that baby’s primary caretaker for a long time. It is much better that she be introduced to recovery and various avenues of support through methadone or buprenorphine treatment than to be left on her own with no support, little guidance, and struggling to find dope on a daily basis.