Category Archives: Heroin

Evzio For Reversal of Opioid Overdose

evzio-naloxoneEvzio is an FDA-approved emergency treatment that counteracts the effects of opioid overdose. It is an “auto-injector” designed to contain a retractable needle and a 0.4 mg dose of naloxone. Naloxone is a powerful opioid antagonist that reverses the effects of overdose with heroin or other opiates. Naloxone has been used throughout the country in the past few years and literally saved hundreds of lives.

evzio-imageKaleo Pharma is the manufacturer of Evzio. The company specializes in innovative solutions for serious and life threatening medical conditions. Kaleo Pharma is based out of Richmond, Virginia, USA.

As has been documented in national media, very potent forms of heroin have become available much of it laced with other opiate derivatives like fentanyl. These combinations have proven lethal in a large number of cases often with younger people being the victims of overdose due to not understanding the extreme potency of the drugs being sold.

Products like Evzio in the hands of family and local emergency response teams can yield life saving interventions within minutes.

When addicted people survive a near fatal overdose, this often acts as a necessary catalyst to enter treatment and to step onto the path of personal recovery. Overdose survivors sometimes reflect on what has happened to them and may realize the pain that their death would have caused their children, friends, and family. The vast majority of overdoses are accidental and are nearly always preventable.

It is important to remember that addiction is an illness and that addicted people can recover, and can go on to live much improved lives when they are ready to change. Evzio will most likely save many people and give them that opportunity to live a life of real recovery.

For more about naloxone

Suboxone Facilitates Safety and Recovery

suboxone-doctorSuboxone is a leading medication in the treatment of opioid dependence and has been available since 2002 when the FDA approved Subutex (buprenorphine hydrochloride) and Suboxone tablets (buprenorphine hydrochloride and naloxone hydrochloride).

Suboxone tablets have since been replaced by the thin sublingual suboxone film that is also dissolved under the tongue. While methadone has been highly successful for several decades, suboxone has expanded the range of options for those suffering with opioid withdrawal.

Fighting off opioid withdrawal is at the core of opioid addiction and is chiefly responsible for the stress that addicted individuals feel as they try to function normally each day. Suboxone not only helps patients eliminate opioid withdrawal sickness and associated cravings, but it also brings the opportunity to function again as an employee, a parent, or a spouse.

Many patients report not only feeling relief from the welcomed absence of withdrawal sickness, but recapturing the focus necessary to make strides in other important areas of their lives. This illustrates the profound advantage that some patients derive from opioid replacement therapy.

There are an increasing number of physicians now providing opioid addiction treatment services and utilizing suboxone due to its effectiveness and patient convenience. Additionally, some traditional methadone clinics are adopting buprenorphine (suboxone) as a second option for their patients.

Suboxone therapy ultimately increases safety for opioid addicted patients since they are less prone to secure opiates illicitly. It may also save them from having to rely on heroin or other potentially high-risk medications (like benzodiazepines) in order to “get by”. Patients are better able to cut ties with those that have provided them opiates illicitly and this is extremely helpful to the recovery process.

Originally, Sildenafil was intended for the treatment of angina or chest pain caused by decreased blood flow to the heart. But then followed the trials, as the drug didn’t provide stated effect. But volunteers’ studies showed an interesting side effect- stable and strong erection which is described at . Other studies conducted around the same time showed that the molecular structure of Sildenafil can play a great role in erection, which encouraged the new studies of the drug for men with erectile dysfunction.

If choosing suboxone, it is important that individuals go the proper route and enroll in therapy with a buprenorphine-approved physician. This cannot be overstated. A doctor specializing in the administration of buprenorphine (suboxone) can provide the necessary assistance to make suboxone therapy effective and to help patients taper down successfully should they decide to discontinue suboxone therapy.

For more on this topic, visit our Suboxone Doctors information page.

You can also perform a comprehensive search of Suboxone Doctors by clicking view the complete list on our Search Clinics By State page.

Pregnancy and Opioid Treatment

pregnancyWhen a woman is pregnant and addicted to opioids, she faces extraordinary stress and very often a wave of judgment from those around her that is emotionally painful and difficult to deal with. The criticism of others is understandable since no one wants to see an unborn baby placed at risk through the mother’s drug use. But this cauldron of angry emotion and public condemnation often overwhelms a pregnant mother, who may already feel guilty, and it pushes her further into isolation and inaction. This isolation only places the mother and unborn baby at greater risk of overdose and possible miscarriage.

Fact: It has been thoroughly researched and the findings conclusive that pregnant opioid-addicted women have a much better chance of carrying their baby to term and having a healthy baby when the mother is receiving medication-assisted treatment. Every day, addicted mothers receiving methadone or buprenorphine give birth to healthy babies that thrive and develop normally.

Methadone and buprenorphine (Subutex) are very different medications compared to heroin and painkillers like oxycodone. Heroin and painkillers manufactured for break-through pain act quickly, but also dissipate quickly. For those with an opioid addiction, this momentary relief from opioid withdrawal does not last long and they are back out there again desperately trying to find more heroin to avoid becoming sick.

With methadone or buprenorphine, mothers are medically stable and able to avoid debilitating cycles of withdrawal as well as the dangerous drug-seeking behaviors and lifestyle that put them and the baby at risk. A woman is already in a state of increased vulnerability when pregnant. If lonely, isolated and forced to go to the street to find dope or pills, she will find herself in dangerous situations and exposed to a drug culture that values money over human life.

This harsh reality is what some women face as they struggle to survive while carrying an unborn child. If in treatment at a methadone clinic or under the supervision of a caring physician who utilizes buprenorphine, the pregnant woman can start the process of personal recovery. She can avoid becoming sick from opioid withdrawal and avoid taking grave risks just to avoid that withdrawal. She can receive emotional support and medical assistance to maximize her health and that of the unborn baby. She can better prepare herself to be a good mom once the baby is born.

There are those who may indignantly exclaim “But the baby will be born addicted”. The reality is that it is much safer for a baby to be born to a mother receiving methadone or buprenorphine than for the baby to be repeatedly exposed to adulterated street heroin and combinations of drugs riddled with unknown contaminants. Think about that. Technically, the baby may be born with some physical dependency, but this is successfully managed all the time by medical professionals across the country. Buprenorphine has been found to have a milder withdrawal syndrome and is utilized successfully in helping infants comfortably detox. Methadone is successfully used for this purpose as well.

It is important to also make a distinction between “addiction” and “dependency”. They are not the same. “Addiction” encompasses the persistent craving for opiates, the mental preoccupation with securing them, and the inappropriate behaviors and lifestyle aberration that develop as people lose control over their ability to choose. “Dependency” can occur with anyone who has been using an opioid for a sustained period of time. Someone who has become “dependent” can readily taper off of the medication and will not be necessarily driven to obsess over drugs or desperately seek them. A baby who is born temporarily dependent on methadone or buprenorphine can be successfully tapered off of the medication. Obviously, a baby does not meet the definition of “addicted” so to use that term is technically inaccurate and misleads the public.

Finally, methadone and buprenorphine are safer for the baby. It’s ultimately about helping that unborn baby to develop normally in the womb and to be born alive, healthy, and with maximum opportunity for a good life. Chances are that the mother will indeed be that baby’s primary caretaker for a long time. It is much better that she be introduced to recovery and various avenues of support through methadone or buprenorphine treatment than to be left on her own with no support, little guidance, and struggling to find dope on a daily basis.

 

Naloxone Reverses Opioid Overdose and Saves Lives

naloxone-kitMore communities across the U.S. are facing the devastation of opioid overdose. The impact on families is profound as they often struggle with questions of “Could we have done more?” and ponder what else must be done to address this growing national epidemic.

Highlighted in the news this week was the heroin overdose death of a Louisville cheerleader and the suspected opioid overdose death of a 27 year old man in North Carolina found slumped behind the wheel of his pick-up truck with an empty bottle of painkillers and a spoon beside him.

Naloxone is an FDA-approved medication that reverses the effects of opioid overdose. It is an opioid antagonist and consequently knocks opiates off of the body’s opioid receptor sites thus reversing central nervous system and respiratory depression which are the most dangerous consequences of opioid overdose. In many cases, naloxone quickly restores breathing and allows overdose victims to regain consciousness in a relatively short period of time. Naloxone is administered by injection or intranasally as a mist.

An increasing number of emergency first responders are now carrying naloxone kits as are some police units in select areas of the country. Local government is now more involved too with new legislation having been proposed in the last year to dramatically increase funding for the provision of naloxone kits.

Ideally, naloxone will one day become readily available without prescription to anyone via their local pharmacy. There is no upside to politicizing something as beneficial as naloxone because it simply saves lives. Note that the medication itself produces no drug high.

Methadone and Other Medications

doc66Methadone is FDA-approved for pain management and the treatment of opioid addiction. Methadone is a relatively safe and highly effective medication when used exactly as prescribed. It is currently in use in the United States and around the world following years of conclusive research on methadone’s efficacy and safety.

It is important for patients receiving methadone to know that it can interact with other central nervous system depressants like alcohol and benzodiazepines such as xanax, klonopin, valium, and librium as well as similarly acting non-benzodiazepine agents like ambien (a popular sleep aid). When methadone is mixed with these other medications, there is an increased risk of sedation and loss of consciousness. In extreme cases, individuals mixing methadone and other CNS depressants have gone into respiratory failure.

For those who have chosen to receive methadone in an opioid treatment program, they will discover that a proper dose of methadone not only eliminates opiate withdrawal & cravings, but will also block the euphoric effects of any other opiates. This is typically a positive side effect in that it discourages illicit opiate use or supplementing with street drugs like heroin. Since methadone binds so well to the brain’s opiate receptor sites, any other opiates that are ingested have no means of creating a euphoria or a high since the body’s opiate receptors are occupied by methadone. This removes the incentive to misuse other opiates and can facilitate the process of recovery. I was ordered by his neuropathologist to treat panic attacks. I began to drink them in half, and then I kiss the pill for the night. I drank a tablet of hours at 8 pm – after half an hour I sleep with a child). The effect is very classy: nothing is interesting, nothing is needed, there is no emotion – everything a person needs is just morally tired.) She accepted Klonopin for about four months. The effect was. Somehow I just did not care about panic attacks). They did not care anymore.

There are instances in which a patient’s physician has prescribed a benzodiazepine for anxiety management while also prescribing methadone. Such decisions should always be accompanied by a thorough discussion with one’s doctor of the potential risks & complications. There are other, safer alternatives for treating anxiety such as Buspar and cognitive therapy. These other options should be considered when a patient is already receiving methadone. In addiction treatment, the use of benzodiazepines for anxiety is typically monitored carefully through increased random urinalysis testing and medication counts.